Deborah L Croteau Selected Research

RecQ Helicases

1/2017	Recent Advances in Understanding Werner Syndrome.
3/2016	Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer.
3/2016	RECQL4 helicase has oncogenic potential in sporadic breast cancers.
1/2016	RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks.
11/2014	The role of RecQ helicases in non-homologous end-joining.
1/2014	Human RecQ helicases in DNA repair, recombination, and replication.
5/2013	Human RECQL5: guarding the crossroads of DNA replication and transcription and providing backup capability.
11/2012	The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients.
11/2012	Human RECQL5 participates in the removal of endogenous DNA damage.
8/2012	RecQ helicases in DNA double strand break repair and telomere maintenance.

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Deborah L Croteau Research Topics

Disease

13	Neoplasms (Cancer) 12/2020 - 10/2010
12	Genomic Instability 10/2019 - 07/2010
9	Mitochondrial Diseases (Mitochondrial Disease) 12/2020 - 05/2011
9	Premature Aging 12/2020 - 09/2009
9	Werner Syndrome (Werner's Syndrome) 11/2019 - 09/2009
8	Rothmund-Thomson Syndrome (Syndrome, Rothmund-Thomson) 01/2020 - 09/2009
7	Alzheimer Disease (Alzheimer's Disease) 11/2021 - 01/2015
7	Cockayne Syndrome (Syndrome, Cockayne) 12/2020 - 06/2008
3	Ischemic Stroke 01/2019 - 09/2012
2	Bites and Stings (Sting) 01/2021 - 01/2021
2	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2021 - 10/2019
2	DNA Repair-Deficiency Disorders (Chromosome Instability Syndromes) 01/2020 - 11/2014
2	Cognitive Dysfunction 01/2018 - 06/2014
2	Breast Neoplasms (Breast Cancer) 03/2016 - 01/2016
2	Inborn Genetic Diseases (Disease, Hereditary) 11/2014 - 05/2013
2	Xeroderma Pigmentosum (Kaposi's Disease) 05/2014 - 06/2008
2	Chromosomal Instability (Chromosome Stability) 05/2013 - 09/2009
2	Bloom Syndrome 05/2013 - 07/2012
1	Inflammation (Inflammations) 01/2021
1	Tauopathies 01/2020
1	Hearing Loss (Hearing Impairment) 01/2020
1	Parkinson Disease (Parkinson's Disease) 01/2019
1	Autosomal Dominant Optic Atrophy (Dominant Optic Atrophy) 01/2019
1	Neuroinflammatory Diseases 01/2018
1	Atrophy 09/2015
1	Stroke (Strokes) 07/2015
1	Ataxia Telangiectasia (Louis Bar Syndrome) 05/2014
1	Neuroblastoma 05/2011
1	autosomal recessive 1 Spinocerebellar ataxia 05/2011
1	Persistent Infection 03/2011
1	Ischemia 02/2011
1	Trichothiodystrophy Syndromes 06/2008

Drug/Important Bio-Agent (IBA)

23	Proteins (Proteins, Gene)FDA Link 12/2020 - 06/2008
17	RecQ HelicasesIBA 01/2017 - 09/2009
16	DNA (Deoxyribonucleic Acid)IBA 01/2021 - 06/2008
5	DNA HelicasesIBA 01/2020 - 08/2012
3	NAD (NADH)IBA 01/2019 - 11/2014
3	A-Form DNA (A-DNA)IBA 01/2018 - 06/2010
3	Deoxyribonuclease (Pyrimidine Dimer)IBA 07/2015 - 06/2010
2	Biomarkers (Surrogate Marker)IBA 01/2021 - 01/2016
2	InterferonsIBA 01/2021 - 01/2021
2	Mitochondrial DNA (mtDNA)IBA 12/2020 - 05/2011
2	ChromatinIBA 01/2020 - 01/2019
2	Biological ProductsIBA 01/2020 - 10/2019
2	Poly(ADP-ribose) Polymerases (Poly ADP Ribose Polymerase)IBA 01/2019 - 01/2019
2	DNA Glycosylases (DNA Glycosylase)IBA 01/2019 - 06/2010
2	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 02/2017 - 01/2015
2	NucleotidesIBA 07/2015 - 05/2014
2	EnzymesIBA 02/2015 - 01/2015
1	Apolipoproteins E (ApoE)IBA 11/2021
1	Pharmaceutical PreparationsIBA 11/2021
1	Amyloid beta-PeptidesIBA 01/2021
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2021
1	NucleolinIBA 01/2020
1	nicotinamide-beta-ribosideIBA 01/2020
1	tau Proteins (tau Protein)IBA 01/2020
1	Amyloid (Amyloid Fibrils)IBA 01/2019
1	3,8-dihydroxy-6H-dibenzo(b,d)pyran-6-oneIBA 01/2019
1	actinoninIBA 01/2019
1	HeterochromatinIBA 01/2019
1	Sirtuin 3IBA 01/2018
1	1,2- di- (4- sulfamidophenyl)- 4- butylpyrazolidine- 3,5- dione (DSB)IBA 12/2017
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 03/2016
1	Type I DNA Topoisomerases (Topoisomerase I)IBA 03/2016
1	CamptothecinIBA 03/2016
1	SirtuinsIBA 01/2016
1	Messenger RNA (mRNA)IBA 01/2016
1	LipidsIBA 09/2015
1	RNA (Ribonucleic Acid)IBA 09/2015
1	EndonucleasesIBA 07/2015
1	X-ray Repair Cross Complementing Protein 1IBA 07/2015
1	thymine glycolIBA 07/2015
1	8-hydroxyguanineIBA 07/2015
1	Sirtuin 1IBA 11/2014
1	Tissue ExtractsIBA 06/2014
1	Citrate (si)-Synthase (Synthase, Citrate)IBA 05/2011
1	2,6- diamino- 4- hydroxy- 5- formamidopyrimidineIBA 02/2011
1	4,6-diamino-5-N-formamidopyrimidine (FAPy)IBA 02/2011
1	Protein Isoforms (Isoforms)IBA 02/2011
1	Bloom syndrome proteinIBA 07/2010
1	5-hydroxyuracilIBA 06/2010
1	PyrimidinesIBA 06/2010
1	5-hydroxycytosineIBA 06/2010
1	PurinesIBA 06/2010

Therapy/Procedure

2	Lasers (Laser) 01/2017 - 01/2013
1	Therapeutics 10/2019
1	Drug Therapy (Chemotherapy) 03/2016